Background and Objectives: To show whether the 2D-array scanning system can be used as a substitute for the MP3-water phantom, we have used a comparison of beam profiles and the percentage depth doses for both electron beams and the photons, also we have confirmed the validation of the results by CMS XiO treatment planning system. Methods: Beam data was obtained for MP3-water phantom and 2D-array scanning system for 6 MV and 15 MV photon beam; and 4, 6, 8, 10, 12 and 15 MeV electron beams generated from  ONCOR Digital Medical Linear accelerator for (2×2cm², 3×3cm², 5×5cm²,10×10cm²,15×15cm²and 20×20cm²) at 10cm depth. CMS XiO treatment planning system was utilized for validation of the obtained data. Results: doses distribution for the two studied systems is compared with uncertainties within the recommended limits. It is found that there's no vital variation in flatness and symmetry obtained from the 2D-Array as compared to the quality MB3-Water Phantom Flatness and symmetry obtained is well at intervals the limit of ±3%. Conclusion: it is concluded that the 2D-Array-729 is used for the routine measuring of the photon beam profiles as alternative to water phantom.