[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: ::
Back to the articles list Back to browse issues page
A pre-exposure to RF-EMF can enhance the immune responses of mice following Salmonella Typhimurium and Klebsiella pneumoniae infections
S. Zarei, S. Tajbakhsh, M. Taheri, H. Mozdarani, A. Jafarzadeh, F. Nouri, S. Nematollahi, S. Dobaradaran, S.M.J. Mortazavi Ph.D.,
Department of Medical Physics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran , mmortazavi@sums.ac.ir
Abstract:   (74 Views)
Background: The question of whether low levels of non-ionizing radiations such as the radiofrequency electromagnetic fields (RF-EMF) can induce the same positive immune responses remains unanswered. This study aimed to investigate the effects of non-ionizing RF-EMF on some parameters of the immune system in an animal model following infection with Salmonella Typhimurium and Klebsiella pneumoniae. Materials and Methods: Male BALB/c mice were exposed to RF-EMFs generated by a common GSM mobile phone for 3 days. Animals were infected with K. pneumonia or S. Typhimurium on the 4th day. On the7th day after injection, blood samples were collected by cardiac puncture. The specific antibodies against bacteria were determined by agglutination method and serum levels of the cytokines were measured using the ELISA method. Moreover, the leukocytes count was measured using a cell counter. Results: The levels of specific antibodies against bacteria were higher in non-irradiated mice compared to irradiated mice. There were no significant differences between the irradiated and non-irradiated mice regarding the total blood leukocyte count. The mean serum levels of IFN-γ and IL-17 after infection with K. pneumoniae were significantly higher in the irradiated mice (p<0.001). Conclusions: Low levels of RF-EMF can stimulate the immune responses in the mice pre-exposed to RF-EMF. This study provides further evidence supporting that exposure to certain levels of RF-EMF can stimulate the immune system. These adaptive responses may be applied to cope with the increased susceptibility of the astronauts to infections during a deep space mission.
Keywords: Salmonella typhimurium, Klebsiella pneumoniae, microwave radiation, IL-17.
Full-Text [PDF 1856 kb]   (15 Downloads)    
Type of Study: Original Research | Subject: Medical Physics
Send email to the article author

Add your comments about this article
Your username or Email:


XML     Print

Back to the articles list Back to browse issues page
International Journal of Radiation Research
Persian site map - English site map - Created in 0.06 seconds with 34 queries by YEKTAWEB 4071