Background: The side effects of therapies such as chemotherapy (CT), radiotherapy (RT) and surgery in cancer patients are very high. For this reason, even when recovery is achieved in cancer, life is often shortened due to the side effects of treatments. Bioresonance treatment (BRT) on cancer is intended to reduce cancer-related complaints such as pain, nausea and weakness or treatment side effects. Materials and Methods: In this study, BRT effects have been evaluated according to the performance status, symptomatic recovery after the therapy in cancer patients treated with the BICOM BRT with or without RT or CT. We used to Ai programs, harmonious inverted and disharmonious inverted (Hi-Di) programs for the treatment of, pain, nosea, dispnea etc. complaints with using local electrods of BICOM machine. Results: A statistically significant difference was found between the treatment response averages of BRT application groups according to ECOG performance (Eastern Cooperative Oncology Group performance) scale. It is understood that the BRT treatment response was obtained later sessions of the group wich have better scoring  (p = 0.005). Conclusion: The treatment response of with worse ECOG performance scoring of patients was better in early sessions than late sessions of BRT. Whereas the response time was shorter than the late responding patients. BRT method decreased to side effets of conventional cancer therapies also increased to the quality of life and palliation of patients.