[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
IJRR Information::
For Authors::
For Reviewers::
Subscription::
News & Events::
Web Mail::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
ISSN
Hard Copy 2322-3243
Online 2345-4229
..
Online Submission
Now you can send your articles to IJRR office using the article submission system.
..

AWT IMAGE

AWT IMAGE

:: Volume 21, Issue 4 (10-2023) ::
Int J Radiat Res 2023, 21(4): 633-637 Back to browse issues page
Observation on the therapeutic effect of chemotherapy combined with Banxia Xiexin decoction on duodenal cancer under CT enhanced scanning
Y. Gou , H. Zhou
Department of General Surgery, The People’s Hospital of Changshou Chongqing, Chongqing, 401220, China (mainland)
Abstract:   (715 Views)
Background: Banxia Xiexin Decoction (BXD) is reported to be effective in the treatment of gastrointestinal diseases. In this work, we evaluated the effects of chemotherapy combined with Banxia Xiexin Decoction on duodenal cancer using Computed tomography (CT) enhanced scanning. Materials and Methods: Totally 80 cases diagnosed with duodenal cancer were selected, and the data of patients were retrospectively analyzed. They were randomly allocated into the treatment and control groups with 40 patients in each group. Participants in the treatment group received serotonin blocker (granisetron) combined with chemotherapy drugs, and oral administration of Banxia Xiexin Decoction to prevent nausea, vomiting and other gastrointestinal reactions. Those in the control group received chemotherapy drugs, combined with serotonin blocker (granisetron). CT enhanced scan, magnetic resonance imaging (MRI) and pathological examination were performed, and pathological diagnosis was used as the gold standard for treatment effect evaluation. Results: For patients in the treatment group, 13 were analyzed, 15 were clear, 9 had no effect, and 3 were negative, with a total effect of 93.50%; For patients in the control group, there are 6 patients with control, 16 patients with obvious results, 12 patients with benefits, and 6 with no benefits, with a total results of 87.00%. All the results were significantly different between the two groups (P<0.05). Conclusion: Banxia Xiexin decoction has the advantages of low cost, obvious benefits, and few side effects in the treatment of nausea and vomiting of duodenal cancer patients, which is suitable for medical treatment.
Keywords: Chinese herbal medicine, Banxia Xiexin Decoction, chemotherapy, CT.
Full-Text [PDF 553 kb]   (370 Downloads)    
Type of Study: Original Research | Subject: Radiation Biology
References
1. 1. Zhang Z, Lei Y, Wang D, et al. (2022) Case Report: A case of advanced duodenal adenocarcinoma in complete remission after chemotherapy combined with targeted therapy and radiotherapy. Frontiers in Oncology, 12: 968110. [DOI:10.3389/fonc.2022.968110] [PMID] []
2. Manur JG and Jain HM (2021) A case of duodenal adenocarcinoma treated with primary chemoradiation. Journal of Cancer Research and Therapeutics, 17(4): 1101-3. [DOI:10.4103/jcrt.JCRT_695_19] [PMID]
3. Yamamoto N, Washimi K, Murakawa M, et al. (2021) Primary Duodenal Carcinoma with Embryonal Carcinoma Features in a Young Man. Case Reports in Gastroenterology, 15(1): 269-75. [DOI:10.1159/000512421] [PMID] []
4. Jiang S, Zhao R, Li Y, et al. (2018) Prognosis and nomogram for predicting postoperative survival of duodenal adenocarcinoma: A retrospective study in China and the SEER database. Scientific Reports, 8(1): 7940. [DOI:10.1038/s41598-018-26145-6] [PMID] []
5. Cloyd JM, George E, Visser BC (2016) Duodenal adenocarcinoma: Advances in diagnosis and surgical management. World Journal of Gastrointestinal Surgery, 8(3): 212-21. [DOI:10.4240/wjgs.v8.i3.212] [PMID] []
6. Meijer LL, Alberga AJ, de Bakker JK, et al. (2018) Outcomes and Treatment Options for Duodenal Adenocarcinoma: A Systematic Review and Meta-Analysis. Annals of Surgical Oncology, 25(9): 2681-92. [DOI:10.1245/s10434-018-6567-6] [PMID] []
7. García-Molina FJ, Mateo-Vallejo F, Franco-Osorio Jde D, et al. (2015) Surgical approach for tumours of the third and fourth part of the duodenum. Distal pancreas-sparing duodenectomy. International Journal of Surgery (London, England), 18: 143-8. [DOI:10.1016/j.ijsu.2015.04.051] [PMID]
8. Teschke R, Wolff A, Frenzel C, et al. (2015) Herbal traditional Chinese medicine and its evidence base in gastrointestinal disorders. World Journal of Gastroenterology, 21(15): 4466-90. [DOI:10.3748/wjg.v21.i15.4466] [PMID] []
9. Song H, Qiu J, Yu C, et al. (2022) Traditional Chinese Medicine prescription Huang-Qi-Jian-Zhong-Tang ameliorates indomethacin-induced duodenal ulcers in rats by affecting NF-κB and STAT signaling pathways. Biomedicine & pharmacotherapy = Biomedecine & Pharmacotherapie, 156: 113866. [DOI:10.1016/j.biopha.2022.113866] [PMID]
10. Wang W, Gu W, He C, et al. (2022) Bioactive components of Banxia Xiexin Decoction for the treatment of gastrointestinal diseases based on flavor-oriented analysis. Journal of ethnopharmacology, 291: 115085. [DOI:10.1016/j.jep.2022.115085] [PMID]
11. Feng X, Xue F, He G, et al. (2021) Banxia xiexin decoction affects drug sensitivity in gastric cancer cells by regulating MGMT expres-sion via IL-6/JAK/STAT3‑mediated PD-L1 activity. International Journal of Molecular Medicine, 48(2):1-11. [DOI:10.3892/ijmm.2021.4998] [PMID] []
12. Su L, Wang MM, Xu MR, et al. (2019) Banxia Xiexin Decoction () Combined with Afatinib in Treatment of Advanced Gallbladder Cancer: Case Report and Literature Review. Chinese Journal of Integrative Medicine, 25(4): 303-6. [DOI:10.1007/s11655-019-3152-1] [PMID]
13. Zhang Z, Jia G, Pan G, et al. (2022) Comparison of the diagnostic efficacy of (68) Ga-FAPI-04 PET/MR and (18)F-FDG PET/CT in patients with pancreatic cancer. European Journal of Nuclear Medicine and Molecular Imaging, 49(8): 2877-88. [DOI:10.1007/s00259-022-05729-5] [PMID]
14. Ando A, Hagiwara Y, Sekiguchi T, et al. (2020) Contrast-enhanced magnetic resonance imaging revealing the joint capsule pathology of a refractory frozen shoulder. The Open Orthopaedics Journal, 14(1):39-45. [DOI:10.2174/1874325002014010039]
15. Hu W, Liu Z, Xiao X, et al. (2020) Comparison of diagnostic efficacy of MRI and PET/CT in lung cancer of mouse with spinal metastasis. Cellular and Molecular Biology (Noisy-le-Grand, France), 66(3): 138-42. [DOI:10.14715/cmb/2020.66.3.21]
16. Jensen KK, Storkholm JH, Chen I, et al. (2022) Long-term results after resection of primary duodenal adenocarcinoma: A retrospective cohort study. International journal of surgery (London, England), 100: 106599. [DOI:10.1016/j.ijsu.2022.106599] [PMID]
17. Lu H, Qin J, Han N, et al. (2018) Banxia Xiexin Decoction Is Effective to Prevent and Control Irinotecan-Induced Delayed Diarrhea in Recurrent Small Cell Lung Cancer. Integrative cancer therapies, 17(4): 1109-14. [DOI:10.1177/1534735418801532] [PMID] []
18. Yan S, Yue Y, Wang J, et al. (2019) Banxia Xiexin decoction, a traditional Chinese medicine, alleviates colon cancer in nude mice. Annals of Translational Medicine, 7(16): 375. [DOI:10.21037/atm.2019.07.26] [PMID] []
19. Feng X, Xue F, He G, et al. (2021) Banxia Xiexin Decoction Inhibits the Expression of PD-L1 Through Multi-Target and Multi-Pathway Regulation of Major Oncogenes in Gastric Cancer. OncoTargets and Therapy, 14: 3297-307. [DOI:10.2147/OTT.S288442] [PMID] []
20. Ji Q, Yang Y, Song X, et al. (2020) Banxia Xiexin Decoction in the treatment of chronic atrophic gastritis: A protocol for systematic review and meta-analysis. Medicine, 99(42): e22110. [DOI:10.1097/MD.0000000000022110] [PMID] []
21. Cao Y, Zheng Y, Niu J, et al. (2020) Efficacy of Banxia Xiexin decoction for chronic atrophic gastritis: A systematic review and meta-analysis. PloS One, 15(10): e0241202. [DOI:10.1371/journal.pone.0241202] [PMID] []
22. Kim K, Chie EK, Jang JY, et al. (2012) Role of adjuvant chemoradiotherapy for duodenal cancer: a single center experience. American Journal of Clinical Oncology, 35(6): 533-6. [DOI:10.1097/COC.0b013e31821dee31] [PMID]
23. Wang J, Yang B, Li L (2019) Effect of Banxia Xiexin decoction combined with weifuchun on serum epidermal growth factor, serum pepsinogen and gastrin expression in patients with chronic atrophic gastritis. Jo Liaoning Coll Tradit Chin Med, 21: 154-7.
24. Ji Q, Luo YQ, Wang WH, et al. (2016) Research advances in traditional Chinese medicine syndromes in cancer patients. Journal of Integrative Medicine, 14(1): 12-21. [DOI:10.1016/S2095-4964(16)60237-6]
25. Tian J, Li M, Liao J, et al. (2013) Chinese herbal medicine banxiaxiexin decoction treating diabetic gastroparesis: a systematic review of randomized controlled trials. Evidence-based complementary and alternative medicine : eCAM, 2013: 749495. [DOI:10.1155/2013/749495] [PMID] []
26. Wang B, Zeng KW, Hong ZF, et al. (2020) Banxia Xiexin Decoction () Treats Diabetic Gastroparesis through PLC-IP(3)-Ca(2+)/NO-cGMP-PKG Signal Pathway. Chinese Journal of Integrative Medicine, 26(11): 833-8. [DOI:10.1007/s11655-020-3077-8] [PMID]
Add your comments about this article
Your username or Email:

CAPTCHA



XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Gou Y, Zhou H. Observation on the therapeutic effect of chemotherapy combined with Banxia Xiexin decoction on duodenal cancer under CT enhanced scanning. Int J Radiat Res 2023; 21 (4) :633-637
URL: http://ijrr.com/article-1-5017-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 21, Issue 4 (10-2023) Back to browse issues page
International Journal of Radiation Research
Persian site map - English site map - Created in 0.06 seconds with 50 queries by YEKTAWEB 4642