[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
IJRR Information::
For Authors::
For Reviewers::
Subscription::
News & Events::
Web Mail::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
ISSN
Hard Copy 2322-3243
Online 2345-4229
..
Online Submission
Now you can send your articles to IJRR office using the article submission system.
..

AWT IMAGE

AWT IMAGE

:: Volume 21, Issue 4 (10-2023) ::
Int J Radiat Res 2023, 21(4): 849-853 Back to browse issues page
High-dose-rate mold brachytherapy for mandibular gingival squamous cell carcinoma in outpatient setting – Initial case report
A. Takeshita , H. Shimamoto , Y. Uchimoto , T. Tsujimoto , T. Miyamoto , S. Kreiborg , S.M. Mallya , M. Oda , T. Hirata , K. Ogawa , H. Shiomi , S. Murakami
Department of Oral and Maxillofacial Radiology, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita, Osaka 565-0871, Japan , shimamoto.hiroaki.dent@osaka-u.ac.jp
Abstract:   (537 Views)
Brachytherapy is often used to treat oral cancer, as it generally yields a good outcome with little oral function loss. In particular, mold brachytherapy is ideally suited for superficial oral cases, such as cancers developing on the gingiva, palate, or buccal mucosa, with little to no bone involvement and thin tissue thickness. Mold brachytherapy including that at a high-dose-rate (HDR) is used to treat gingival cancer, though hospitalization is the typical treatment setting. Reported here are details of HDR mold brachytherapy performed in an outpatient setting for a mandibular gingival case of squamous cell carcinoma (SCC). Mandibular gingival SCC in a 71-year-old man was treated as an outpatient using HDR mold brachytherapy (54 Gy in 9 fractions, 5 days). After receiving mold treatment for thirty months, there was no sign of recurrence or metastasis. To our knowledge, this is the first report of HDR mold brachytherapy in an outpatient setting for treating mandibular gingival cancer.
Keywords: Gingival cancer, radiation therapy, mold brachytherapy, outpatient.
Full-Text [PDF 852 kb]   (303 Downloads)    
Type of Study: Case Report | Subject: Radiation Biology
References
1. 1. Unetsubo T, Matsuzaki H, Takemoto M, et al. (2015) High-dose-rate brachytherapy using molds for lip and oral cavity tumors. Radiat Oncol, 10: 81. [DOI:10.1186/s13014-015-0390-z] [PMID] []
2. Yamazaki H, Yoshida K, Yoshioka Y, et al. (2013) High dose rate brachytherapy for oral cancer. J Radiat Res, 54: 1-17. [DOI:10.1093/jrr/rrs103] [PMID] []
3. Wong G, Cirino ET, Ladd RO, et al. (2015) Use of customized intraoral mold high-dose-rate brachytherapy in the treatment of oral cavity cancer in an elderly patient. Pract Radiat Oncol, 5: 74-78. [DOI:10.1016/j.prro.2014.05.007] [PMID]
4. Ariji E, Hayashi N, Kimura Y, et al. (1999) Customized mold brachytherapy for oral carcinomas through use of high-dose-rate remote after loading apparatus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 87: 508-512. [DOI:10.1016/S1079-2104(99)70253-2] [PMID]
5. Matsuzaki H, Takemoto M, Hara M, et al. (2012) Two-piece customized mold technique for high-dose-rate brachytherapy on cancers of the buccal mucosa and lip. Oral Surg Oral Med Oral Pathol Oral Radiol, 113: 118-125. [DOI:10.1016/j.tripleo.2011.06.038] [PMID]
6. Nishimura Y, Yokoe Y, Nagata Y, et al. (1998) High-dose-rate brachytherapy using molds for oral cavity cancer: The technique and its limitations. Int J Clin Oncol, 3: 351-356. [DOI:10.1007/BF00539212]
7. Prisciandaro JI, Foote RL, Herman MG, et al. (2005) A buccal mucosa carcinoma treated with high dose rate brachytherapy. J Appl Clin Madical Phys, 6: 8-12. https://doi.org/10.1120/jacmp.2023.25318 [DOI:10.1120/jacmp.v6i1.2064]
8. Jolly DE and Nag S (1992) Technique for construction of dental molds for high-dose-rate remote brachytherapy. Spec Care Dentist, 12: 219-224. [DOI:10.1111/j.1754-4505.1992.tb00452.x] [PMID]
9. Chatani M, Tsuboi K, Yagi M, et al. (2012) High dose rate brachytherapy using molds after chemoradiotherapy for oral cavity cancer. Jpn J Radiol, 30:40-44. [DOI:10.1007/s11604-011-0005-z] [PMID]
10. Garrán C, Montesdeoca N, Martínez-Monge R (2008) Treatment of upper gum carcinoma with high-dose-rate customized-mold brachytherapy. Brachytherapy, 7: 267-269. [DOI:10.1016/j.brachy.2008.04.001] [PMID]
11. Obinata K, Ohmori K, Shirato H, Nakamura M (2007) Experience of high-dose-rate brachytherapy for head and neck cancer treated by a customized intraoral mold technique. Radiat Med, 25: 181-186. [DOI:10.1007/s11604-007-0121-y] [PMID]
12. Kudoh T, Ikushima H, Kudoh K, et al. (2010) High-dose-rate brachytherapy for patients with maxillary gingival carcinoma using a novel customized intraoral mold technique. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 109: e102-e108. [DOI:10.1016/j.tripleo.2009.10.019] [PMID]
13. Cengiz M, Ozyar E, Ersu B, et al. (1999) High dose rate mold brachytherapy of early gingival carcinoma: a clinical report. J Prosthet Dent, 82: 512-514. [DOI:10.1016/S0022-3913(99)70047-8] [PMID]
14. Head and Neck cancers, Version 2. NCCN Clinical Practice Guidelines in Oncology. (2022). Available online: https://www.nccn.org. Accessed 11th November 2022.
15. Khan FM (2010) The physics of radiation therapy. 4th ed. Lippincott Williams & Wilkins, Philadelphia p. 316.
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA



XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Takeshita A, Shimamoto H, Uchimoto Y, Tsujimoto T, Miyamoto T, Kreiborg S, et al . High-dose-rate mold brachytherapy for mandibular gingival squamous cell carcinoma in outpatient setting – Initial case report. Int J Radiat Res 2023; 21 (4) :849-853
URL: http://ijrr.com/article-1-5096-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 21, Issue 4 (10-2023) Back to browse issues page
International Journal of Radiation Research
Persian site map - English site map - Created in 0.05 seconds with 50 queries by YEKTAWEB 4642