[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
IJRR Information::
For Authors::
For Reviewers::
News & Events::
Web Mail::
Search in website

Advanced Search
Receive site information
Enter your Email in the following box to receive the site news and information.
Hard Copy 2322-3243
Online 2345-4229
Online Submission
Now you can send your articles to IJRR office using the article submission system.



:: Volume 22, Issue 2 (4-2024) ::
Int J Radiat Res 2024, 22(2): 265-270 Back to browse issues page
Maximum PET/CT 18F-FDG uptake of lymph nodes predicts prognosis in esophageal squamous cell carcinoma
J. Deng , W. Ren , J. Shen , L. Ma , K. Zhao
Department of Radiation Oncology, Fudan University Shanghai Cancer Center; Shanghai, 200032, China , zhaokuaile1153@163.com
Abstract:   (371 Views)
Background: In the present study, PET/CT imaging characteristics were explored to investigate the prognostic value of 18F–fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in oesophageal squamous cell carcinoma (ESCC). Materials and Methods: Baseline PET/CT and clinical characteristics were collected in 125 patients with ESCC treated with radical radiotherapy from 2007–2016. The maximum standardized uptake value (SUVmax) of the primary gross tumour (SUVmax-T) and metastatic lymph nodes (SUVmax-N) were separately measured using X-tile. Overall survival (OS) and progression free survival (PFS) were estimated according to the Kaplan–Meier method. A multivariate Cox model was used to establish the independent prognostic factors. Results: The gross tumours presented higher 18F-FDG uptake than normal tissues. The OS and PFS did not show significant differences between patients with different SUVmax-T values. However, patients with SUVmax-N ≥ 11 had a significantly worse OS and PFS than those with SUVmax-N <11 (P<0.05). A weak correlation was observed in SUVmax-T and SUVmax-N. The OS and PFS of patients with PET-negative lymph nodes (LNs) were significantly better than those with PET-positive LNs. However, the OS and PFS of patients with one or two PET-positive LNs were not significantly better than those with more than two PET-positive LNs. In multivariate analysis, SUVmax-N was suggested to be an independent predictor for OS and PFS. Conclusions: SUVmax-N, but not SUVmax-T, is an independent prognostic indicator for patients with ESCC.
Keywords: SUV, positron emission tomography, metabolic lymph node, survival.
Full-Text [PDF 833 kb]   (52 Downloads)    
Type of Study: Original Research | Subject: Radiation Biology
Send email to the article author

Add your comments about this article
Your username or Email:


XML     Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Deng J, Ren W, Shen J, Ma L, Zhao K. Maximum PET/CT 18F-FDG uptake of lymph nodes predicts prognosis in esophageal squamous cell carcinoma. Int J Radiat Res 2024; 22 (2) :265-270
URL: http://ijrr.com/article-1-5363-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 22, Issue 2 (4-2024) Back to browse issues page
International Journal of Radiation Research
Persian site map - English site map - Created in 0.05 seconds with 50 queries by YEKTAWEB 4652