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AWT IMAGE

AWT IMAGE

:: Volume 22, Issue 3 (7-2024) ::
Int J Radiat Res 2024, 22(3): 573-578 Back to browse issues page
The Application of 3.0 T magnetic resonance perfusion-weighted imaging in the differentiation and grading of brain gliomas
L. Zhang , M. Sun
Department of Magnetic Resonance Imaging, Cangzhou Central Hospital, No. 16 Xinhua West Road, Cangzhou City 061001, Hebei Province, China , Smin_1201@163.com
Abstract:   (944 Views)
Background: To investigate the value of 3.0T magnetic resonance perfusion-weighted imaging (PWI) in the preoperative differential diagnosis and grading assessment of gliomas. Materials and Methods: The PWI features of 23 single brain metastases and 73 gliomas (32 low-grade and 41 high-grade) were retrospectively analyzed with postoperative pathological findings. The cerebral blood volume (CBV) values of the tumour parenchyma, the peritumoral oedema area and the contralateral normal brain tissue were measured, and the relative CBV (rCBV) values were calculated and statistically analysed. Results: A total of 96 patients, comprising 66 men and 30 women with a mean age of 47 ± 11 years, were included in the study. The time-signal curves of gliomas of different grades obtained by magnetic resonance perfusion have different characteristics. The rCBV values for tumor parenchyma and peritumoral edema were higher in the high-grade glioma group than in the low-grade glioma group and the single brain metastasis group ([6.01 ± 1.64] vs [2.16 ± 0.87] vs [4.37 ± 1.03]) and ([1.82 ± 0.47] vs [0.79 ± 0.34] vs [0.81 ± 0.21]), and the differences were significant (p < 0.05). The rCBV value of the tumour parenchyma in the single brain metastasis group was higher than that in the low-grade glioma group ([4.37 ± 1.03] vs [2.16 ± 0.87]), and the difference was significant (p < 0.05). Conclusion: Magnetic resonance PWI has high clinical value in the preoperative diagnosis and grading evaluation of gliomas.
Keywords: Perfusion Weighted MRI, glioma, neoplasm grading, diagnosis.
Full-Text [PDF 861 kb]   (244 Downloads)    
Type of Study: Original Research | Subject: Radiation Biology
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Zhang L, Sun M. The Application of 3.0 T magnetic resonance perfusion-weighted imaging in the differentiation and grading of brain gliomas. Int J Radiat Res 2024; 22 (3) :573-578
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Volume 22, Issue 3 (7-2024) Back to browse issues page
International Journal of Radiation Research
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