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Study on the relationship between abnormal imaging manifestations of adipose tissue around the primary tumor of colon cancer, genomics and recurrence probability
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Q. Wang   , Z. Wang , L. Liu , H. Wang |
| Department of General Surgery, Tianjin Haihe Hospital, Tianjin, China |
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Abstract: (171 Views) |
Background: This study aims to explore the relationship between abnormal imaging manifestations of adipose tissue around the primary tumor of colon cancer, genomics, and recurrence probability, in order to deepen our understanding of the pathological characteristics and molecular mechanisms of colon cancer. Materials and Methods: We collected imaging data of a group of colon cancer patients and obtained relevant genetic information through genomic analysis. Statistical methods were used to quantitatively analyze the abnormal imaging manifestations of adipose tissue around the primary tumor of colon cancer. At the same time, the patient's clinical course is followed to assess the probability of recurrence. Results: The study found that abnormal imaging manifestations of adipose tissue surrounding primary colon cancer tumors were significantly associated with specific gene mutations. Some specific genetic mutations are positively correlated with abnormal signals on imaging, while others are negatively correlated. Furthermore, after long-term follow-up, we observed a relatively higher probability of recurrence in patients with genetic variants associated with imaging abnormalities. Conclusion: The abnormal imaging manifestations of adipose tissue around the primary tumor of colon cancer can be used as one of the auxiliary indicators for molecular classification of colon cancer. The association between specific genetic variants and imaging abnormalities suggests possible molecular mechanisms and provides new clues for personalized treatment. Furthermore, the association of imaging abnormalities with recurrence probability emphasizes its potential importance in prognostic assessment. |
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| Keywords: Colon cancer, adipose tissue, imaging, genomics. |
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Full-Text [PDF 818 kb]
(29 Downloads)
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Type of Study: Original Research |
Subject:
Radiation Biology
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