|
Effects of laparoscopic ultrasound-guided microwave ablation in combination with surgical resection on liver function and immune function in primary liver cancer patients
|
L. Zhu   , L. Chen , C. Du , N. Tao , J. Pan |
| Department of Ultrasonic Medicine, The First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi, China , LICHEN7006@163.com |
|
|
Abstract: (55 Views) |
Background: To investigate the effects of laparoscopic ultrasound (LUS)-guided microwave ablation (MWA) combined with surgical resection on liver function and immune function of primary liver cancer (PLC) patients. Materials and Methods: Clinical data of 100 patients with PLC after surgery in our hospital from January 2021 to December 2023 were retrospectively analyzed, and divided into laparoscopic hepatectomy (LH group) and laparoscopic ultrasound-guided microwave ablation combined with laparoscopic hepatectomy (LMWA+LH group). Clinical indicators, clinical efficacy, liver function, tumor markers, immune function, incidence of complications, postoperative overall survival rate along with tumor free survival rate between groups were compared. Results: Compared with the LH group, the intraoperative blood loss and postoperative hospital stay was decreased in the LMWA+LH group (P<0.05). Total effective rate of the LMWA+LH group was 90.00%, higher than the 70.00% in LH group (P<0.05). After therapy, reduction in aspartate alanine aminotransferase (ALT), aminotransferase (AST), total bilirubin (TBIL), and the elevation in albumin (ALB) in the LMWA+LH group were more obvious (P<0.05). The LMWA+LH group showed more obvious elevation in CD4+ and CD4+/CD8+ levels and reduction in CD8+ level relative to the LH group (P<0.05). The complication incidence showed no statistical difference between groups (P>0.05). Postoperative survival and tumor free survival rates in the LMWA+LH group were higher than LH group (P<0.05). Conclusion: Laparoscopic ultrasound-guided microwave ablation combined with surgical resection promotes the postoperative recovery, improves liver function and immune function and improves patient survival rate, which might provide guidance for clinical practice. |
|
| Keywords: IMRT, Primary liver cancer, ultrasonography, microwave ablation, hepatectomy, liver function, immune function. |
|
|
Full-Text [PDF 856 kb]
(30 Downloads)
|
|
Type of Study: Original Research |
Subject:
Radiation Biology
|
|
|
|
|
|
|
| Send email to the article author |
|
|
|
| Add your comments about this article |
|
|
|
