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Liu J, Qian J, Ma J, Tang H, Ding J, Tong Y. Using ultrasound-guided fine needle aspiration cytology with ultrasound to diagnose benign and malignant thyroid nodules. Int J Radiat Res 2025; 23 (3) :607-612 URL: http://ijrr.com/article-1-6577-en.html
Ultrasound Department, Tongling Municipal Hospital, Tongling, Anhui Province, China , 13965238978@163.com
Abstract: (573 Views)
Background: Thyroid nodules are common and can be benign or malignant. Ultrasound-guided fine needle aspiration cytology (USG-guided FNAC) is a new method for differentiating these nodules, but previous studies have yet to provide consistent conclusions. The aim of the study was to explore the effectiveness of USG-guided FNAC combined with ultrasonography in diagnosing benign and malignant thyroid nodules. Materials and Methods: The study involved 87 patients who underwent thyroid ultrasound and USG-guided FNAC. The results were compared with surgical and pathological findings, and the diagnostic efficiency was analyzed using ROC curves. Results: Among the 87 thyroid nodules, 22 were malignant, and 53 were benign. USG-guided FNAC alone diagnosed 34 malignant and 58 benign cases, while the combined method diagnosed 25 malignant and 63 benign cases. The ROC curve analysis showed that the combined method had a higher area under the curve (AUC) compared to ultrasound or FNAC alone, indicating better diagnostic accuracy. Conclusion: Combining USG-guided FNAC with ultrasound improves the sensitivity of preoperative differential diagnosis of benign and malignant thyroid nodules.
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