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CT-based evaluation of negative pressure sinus therapy in upper airway cough syndrome: Insights into airway remodeling and tumor detection
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S. Zhang   , M. Xu , X. Shen , J. Ke |
| Department of Otolaryngology, Sanmen People's Hospital, Taizhou City, Zhejiang Province, China , kejuying@zjsmyy.com |
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Abstract: (54 Views) |
Background: Upper airway cough syndrome (UACS) is a common condition marked by chronic cough, nasal congestion, and throat irritation. Standard treatments-including antihistamines, decongestants, and corticosteroids-often yield limited relief. Sinus Negative Pressure Exchange (SNPE) technology has emerged as a novel approach that may enhance sinonasal drainage and mucociliary function. CT imaging provides structural insights and may aid in the detection of sinus tumors. Materials and Methods: This retrospective study evaluated patients with UACS treated using SNPE technology. Symptom severity-cough frequency, nasal blockage, and throat discomfort-was assessed before and after treatment. CT scans were used to assess anatomical changes and to identify any incidental sinus tumors. Logistic regression was used to explore factors associated with clinical response. Results: Patients undergoing SNPE therapy showed significant improvement in cough and nasal congestion. CT scans demonstrated better sinus aeration and drainage post-treatment, supporting the physiological benefits of SNPE. In several cases, clearer imaging enabled incidental detection of sinus tumors, suggesting a potential diagnostic advantage. Regression analysis confirmed a strong association between SNPE use and symptom relief, influenced by baseline severity and comorbidities. Conclusion: SNPE technology shows promise as a dual-purpose intervention for UACS—offering both symptomatic relief and improved radiologic visualization. These findings support SNPE's potential role in managing UACS and facilitating incidental sinus tumor detection. Larger prospective studies are recommended to confirm these outcomes and assess broader clinical implications. |
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| Keywords: Cough, upper respiratory tract diseases, negative-pressure therapy, CT imaging, sinus neoplasms, treatment outcomes. |
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Full-Text [PDF 634 kb]
(7 Downloads)
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Type of Study: Short Report |
Subject:
Radiation Biology
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