Department of Anesthesiology and Surgery, Jianhu County People's Hospital, Yancheng 224700, Jiangsu Province, China , 13961903707@163.com
Abstract: (594 Views)
Background:Preoperative pelvic radiotherapy for rectal cancer can induce tissue fibrosis and impair cardiopulmonary reserve, complicating perioperative management. Modified concave lithotomy positioning may help mitigate these challenges. This study evaluated the influence of preoperative radiotherapy and modified concave lithotomy position on intraoperative respiratory mechanics and hemodynamics in rectal cancer patients. Materials and Methods: Eighty patients with rectal cancer who had received standardized neoadjuvant radiotherapy were randomly divided into two groups: observation group (modified concave lithotomy position) and control group (traditional lithotomy position). Respiratory and circulatory parameters were recorded at key intraoperative time points, along with operation time, blood loss, complications, and recovery indicators. Results: At 30 min after surgery through the end of operation, peak inspiratory pressure, plateau pressure, and mean airway pressure were significantly lower, while dynamic and static lung compliance were higher in the modified position group. Heart rate and central venous pressure were lower, and mean arterial pressure was higher in the modified group (P<0.05). Operation time, blood loss, and complication rates were reduced, with faster postoperative recovery. Subgroup analysis indicated that patients with radiation-induced pelvic fibrosis had decreased lung compliance overall, but the modified position partially alleviated this effect. Conclusion: In rectal cancer patients following preoperative radiotherapy, modified concave lithotomy positioning improves intraoperative respiratory mechanics, stabilizes hemodynamics, and promotes safer perioperative outcomes. These findings emphasize the importance of individualized positioning strategies for radiotherapy-treated surgical patients.
1. Zhang T (2025) Global regional, and national trends in colorectal cancer burden from 1990 to 2021 and projections to 2040. Front Oncol, 14: 1466159. [DOI:10.3389/fonc.2024.1466159]
2. Jiang X, Lv G, Yuan J, Lu K (2025) Colorectal cancer burden, trends, and risk factors in China: rising incidence and disparities in the last 3 decades. Lancet Reg Health West Pac, 55(Suppl 1): 101427. [DOI:10.1016/j.lanwpc.2024.101427]
3. Zhan S, Zhu Z, Yu H, Xia Y, Zhu Y, Wu F, et al. (2024) Comparison of therapeutic effects between conventional 2D laparoscopy and 3D laparoscopy in the treatment of colorectal cancer: a systematic review and meta-analysis. Am Surg, 90(11): 3102-3112. [DOI:10.1177/00031348241257464]
4. Nguyen TX and Pham NH (2023) Three-dimensional laparoscopic surgery for colorectal cancer: a 2-year follow-up study at Hue Central Hospital. Surg Open Sci, 17: 35-39. [DOI:10.1016/j.sopen.2023.12.007]
5. Zhang Y, Zhu J, Xi C, Wang G (2025) Effect of driving pressure-guided individualized positive end-expiratory pressure (PEEP) ventilation strategy on postoperative atelectasis in patients undergoing laparoscopic surgery as assessed by ultrasonography: study protocol for a prospective randomized controlled trial. Trials, 26(1): 106. [DOI:10.1186/s13063-025-08819-5]
6. Hara K, Ichihara K, Yamaguchi M, Takeshita H, Kuroki T (2022) Effect of intraoperative operating table rotation on lower limb perfusion index in patients in the lithotomy position. Medicine (Baltimore), 101(38): e30412. [DOI:10.1097/MD.0000000000030677]
7. Yukizawa Y, Kamono E, Takagawa S, Hirotomi K, Higashihira S, Choe H, et al. (2024) Evaluation of the postoperative risk of deep tissue injury to the lower extremities following surgery in the lithotomy position. Cureus, 16(4): e57413. [DOI:10.7759/cureus.57413]
8. Zhong G, Chen Z, Li Z, Zhao B, Deng J (2024) Transanal intersphincteric under direct view in the jackknife position combined with laparoscopic total mesorectal excision for treating ultra-low rectal cancer. Front Surg, 11: 1419675. [DOI:10.3389/fsurg.2024.1419675]
9. Zheng B, Wang B, Li Z, Qu Y, Qiu J (2024) A modified method for precise anastomosis during laparoscopic low anterior resection for rectal cancer: the first clinical experience and application. BMC Surg, 24(1): 50. [DOI:10.1186/s12893-024-02335-0]
10. Cao L, Liu M, Wang Z, Xu Z, Sun L, Xu P, et al. (2024) Modified dorsal recumbent position versus lithotomy position for flexible ureteroscopic lithotomy: a multicenter prospective randomized controlled clinical trial. Transl Androl Urol, 13(8): 1388-1394. [DOI:10.21037/tau-24-3]
11. Ranganathan P, Jiwnani S, Ashok A, Purwar P, Karimundackal G, Parab S, et al. (2025) Predicting pulmonary complications after esophagectomy: a retrospective cohort study. Indian J Cancer, 62(1): 135-141. [DOI:10.4103/ijc.ijc_67_22]
12. Albert NL, Preusser M, Traub-Weidinger T, Tolboom N, Law I, Palmer JD, et al. (2024) Joint EANM/EANO/RANO/SNMMI practice guideline/procedure standards for diagnostics and therapy (theranostics) of meningiomas using radiolabeled somatostatin receptor ligands: version 1.0. Eur J Nucl Med Mol Imaging, 51(12): 3662-3679. [DOI:10.1007/s00259-024-06783-x]
13. Wen C, Qi Y, Xiang Y, Pang Q, Xiao J, An R (2025) Effect of pressure-controlled ventilation and volume-controlled ventilation for laparoscopic surgery in the Trendelenburg position: a systematic review and meta-analysis. Perioper Med (Lond), 14(1):56. [DOI:10.1186/s13741-025-00540-w]
14. Griva P, Talliou C, Rougeris L, Samara D, Panagouli K, Varvarousi G, et al. (2024) Restoration of pulmonary compliance after laparoscopic gynecologic surgery using a recruitment maneuver. J Pers Med, 14(5): 451. [DOI:10.3390/jpm14050451]
15. Bogár L, Domokos K, Csontos C, Sütő B (2024) The impact of pneumoperitoneum on mean expiratory flow rate: observational insights from patients with healthy lungs. Diagnostics (Basel), 14(21): 2375. [DOI:10.3390/diagnostics14212375]
16. Rezoagli E, Bastia L, Brochard L, Bellani G (2023) Physical manoeuvres in patients with ARDS and low compliance: bedside approaches to detect lung hyperinflation and optimise mechanical ventilation. Eur Respir J, 61(5): 2202169. [DOI:10.1183/13993003.02169-2022]
17. Likhvantsev VV, Landoni G, Berikashvili LB, Polyakov PA, Yadgarov MY, Ryzhkov PV, et al. (2025) Hemodynamic impact of the Trendelenburg position: a systematic review and meta-analysis. J Cardiothorac Vasc Anesth, 39(1): 256-265. [DOI:10.1053/j.jvca.2024.10.001]
18. He H, Gruartmoner G, Ince Y, van Berge Henegouwen MI, Gisbertz SS, Geerts BF, et al. (2018) Effect of pneumoperitoneum and steep reverse-Trendelenburg position on mean systemic filling pressure, venous return, and microcirculation during esophagectomy. J Thorac Dis, 10(6): 3399-3408. [DOI:10.21037/jtd.2018.05.169]
19. Kılınç E, Yildirim SA, Ulugöl H, Büyüköner EE, Güçyetmez B, Toraman F (2023) The evaluation of cardiac functions in deep Trendelenburg position during robotic-assisted laparoscopic prostatectomy. Front Med, 10: 1273180. [DOI:10.3389/fmed.2023.1273180]
20. Kitazawa M, Nakamura S, Yamamoto Y, Miyazaki S, Hondo N, Kataoka M, et al. (2025) Utility of high-positioning pelvic pads in laparoscopic sigmoid colon and rectal surgeries. In-vivo, 39(2): 1078-1085. [DOI:10.21873/invivo.13912]
21. Uzoma CC, Shepherd AI, Saynor ZL, Khan JS, Piozzi GN, Duhoky R, et al. (2025) Head-down tilt lithotomy position and well-leg compartment syndrome: an international survey of current practice. Colorectal Dis, 27(6): e70134. [DOI:10.1111/codi.70134]
22. Kusunoki C, Uemura M, Takeda M, Sekido Y, Hata T, Hamabe A, et al. (2024) Assessing risk factors for elevated creatine kinase levels as an indicator of compartment syndrome following laparoscopic or robot-assisted colorectal cancer surgery in the lithotomy-Trendelenburg position. Surg Endosc, 38(10): 6139-6145. [DOI:10.1007/s00464-024-11209-8]
23. Van Wicklin SA (2020) Systematic review and meta-analysis of prone position on intraocular pressure in adults undergoing surgery. Int J Spine Surg, 14(2): 195-208. [DOI:10.14444/7029]
24. Liu H (2023) Association between sleep duration and depression: a Mendelian randomization analysis. J Affect Disord, 335: 152-154. [DOI:10.1016/j.jad.2023.05.020]
25. Li R, Mukherjee MB, Jin Z, Liu H, Lin K, Liu Q, et al. (2023) The potential effect of general anesthetics in cancer surgery: meta-analysis of postoperative metastasis and inflammatory cytokines. Cancers (Basel), 15(10): 2759. [DOI:10.3390/cancers15102759]
26. Sanduqji IA, Ballourah W, Tashkandi S, Essa M, Jastaniah W, Alghimlas I, et al. (2025) Unraveling the prognostic role of t(1;19) in pediatric pre-B acute lymphoblastic leukemia: insights from a Saudi nationwide cohort. Cancer Genet, 290-291: 1-5. [DOI:10.1016/j.cancergen.2024.10.003]
Cui H, Qiao T, Zhu X. Impact of modified concave lithotomy position on respiratory mechanics and hemodynamics in patients undergoing three-dimensional laparoscopic radical resection and radiotherapy for rectal cancer. Int J Radiat Res 2026; 24 (3) :599-608 URL: http://ijrr.com/article-1-7169-en.html