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:: Volume 12, Issue 2 (4-2014) ::
Int J Radiat Res 2014, 12(2): 151-160 Back to browse issues page
Effect of uniform magnetic field on dose distribution in the breast radiotherapy
A.D. Esmaeeli Dr. , M. Pouladian, A.S. Monfared, S.R. Mahdavi, D. Moslemi
Department of Medical Radiation Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran , ali_esmaeeli_d@yahoo.com
Abstract:   (10074 Views)

Background: To reduce the dose to normal tissues surrounding the treated breast, a uniform magnetic field was used within a humanoid phantom in breast radiotherapy. Materials and Methods: Monte Carlo simulations were performed with GEANT4, irradiating humanoid phantoms in a magnetic field. To reconstruct phantoms, computed tomography (CT) data slices of four patients were used for the Monte Carlo simulations. All of them had left breast cancer either or not mastectomy. In the simulations, the planning and methods of chest wall irradiation were similar to the actual clinical planning. Results: Utilizing magnetic field will help to produce uniform dose distribution to the breast with a sharp dose-volume histogram (DVH) curve for the planning target volume (PTV), however, for the ipsilateral lung and chest wall skin the mean dose was reduced by a mean of 16% and 12% at 1.5 T, and 9% and 7% at 3 T, respectively. The magnetic field was shown to restrict the lateral spread of secondary electrons to the contralateral organs, resulting in significient dose reductions to the contralateral breast (CB) and contralateral chest wall skin (CCWS) by a mean (range) of 28% (21-37%) and 58% (44-75%) at 1.5 T, and 48% (32-81) and 66% (54-73%) at 3 T, respectively. Conclusion: The simulations established that the magnetic field can reduce the dose to the internal and contralateral tissues and increase it to the PTV with sharper edge DVH curve.

Keywords: ERE, magnetic field, breast, GEANT4
Full-Text [PDF 1182 kb]   (2143 Downloads)    
Type of Study: Original Research | Subject: Radiation Biology
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Esmaeeli A, Pouladian M, Monfared A, Mahdavi S, Moslemi D. Effect of uniform magnetic field on dose distribution in the breast radiotherapy. Int J Radiat Res. 2014; 12 (2) :151-160
URL: http://ijrr.com/article-1-1225-en.html

Volume 12, Issue 2 (4-2014) Back to browse issues page
International Journal of Radiation Research
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