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:: Volume 3, Issue 4 (March 2006) ::
Int J Radiat Res 2006, 3(4): 199-202 Back to browse issues page
Unusual presentation of gestational trophoblastic neoplasm: Report of two cases
F.Amouzegar Hashemi , F. Ghaemmaghami, N. Behtash
, amoozfar@sina.tums.ac.ir
Abstract:   (12853 Views)

  Abstract: Gestational Trophoblastic Neoplasm (GTN) is among rare human tumors which can be observed with widespread metastasis. Two young patients with emergent neurologic symptoms with no gynecological problems are presented in this report. GTN was later diagnosed in both cases with brain metastasis. The first case: A 22 years old patient, admitted to the infectious disease ward, with probable diagnosis of Encephalitis. After brain CT scan and measurement of β human chorionic gonadotropin (βhCG), GTN with brain metastasis was confirmed. The second case: A 33 years old patient who underwent craniotomy due to hemorrhagic brain tumor in neurosurgery department. Brain metastatic GTN was confirmed by histological examinations. Both cases received multiagent chemotherapy concurrent with whole brain irradiation of 3000 cGy in 10 fractions (F) within a period of 2 weeks, and chemotherapy was continued for additional course. The patients were both well after about 22 months. Diagnosis of GTN should be considered in any woman of reproductive age.

Keywords: Brain metastatic GTN, choriocarcinoma, multiagent chemotherapy, WBRT
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Type of Study: Case Report |
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F.Amouzegar Hashemi, F. Ghaemmaghami, N. Behtash. Unusual presentation of gestational trophoblastic neoplasm: Report of two cases. Int J Radiat Res. 2006; 3 (4) :199-202
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Volume 3, Issue 4 (March 2006) Back to browse issues page
International Journal of Radiation Research
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