[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
IJRR Information::
For Authors::
For Reviewers::
Subscription::
News & Events::
Web Mail::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
ISSN
Hard Copy 2322-3243
Online 2345-4229
..
Online Submission
Now you can send your articles to IJRR office using the article submission system.
..

AWT IMAGE

AWT IMAGE

:: Volume 19, Issue 2 (4-2021) ::
Int J Radiat Res 2021, 19(2): 251-257 Back to browse issues page
Effects of modulation factors in breast cancer treatment with helical tomotherapy
S.B. Zincircioglu , M.H. Dogan
Department of Radiation Oncology, Dicle University Faculty of Medicine, Diyarbakir, Turkey , sbzoglu@yahoo.com
Abstract:   (1847 Views)
Background: The aim of this study was to compare the dosimetric values of TomoHelical (TH) plans using modulation factors 3 and 5 in patients with breast cancer. Materials and Methods: Two different radiotherapy treatment plans, including modulation factors 3 and 5, were generated retrospectively for 12 consecutive intact breast cancer patients. Twelve different plans in terms of the modulation factor were generated. Other optimization parameters (i.e., pitch and field width) were the same for all plans. Results: No differences were found between the conformity index (CI) and homogeneity index (HI) values of both plans (p>0.05). The values of D mean, V5, and V20 of the ipsilateral lung in the TomoHelical plan with modulation factor 5 (TH5) were significantly lower than with modulation factor 3 (TH3) for all 12 patients (4.9 Gy, 20.14%, 3.23%. Vs, 10.95 Gy, 58.9%, 18.7%; p=0.01, p=0.00, p=0.002, respectively). Also, the values of Dmean and V5 of the heart in TH5 were significantly lower than in TH3 (6.45 Gy, 34.33%, vs. 7.12 Gy, 64.22%; p=0.004, p=0.00, respectively). Conclusion: Both the TH5 and TH3 plans provided adequate coverage of the intact breast. TH5 delivered a decreased dose to the ipsilateral organs at risk (OARs), especially in the lung and heart volume, which is the main cause of long-term toxicity. The novelty of this work is the obvious reduction in same-sided lung volume irradiation by increasing the modulation factor.
Keywords: Breast cancer, modulation factor, irradiation.
Full-Text [PDF 1517 kb]   (839 Downloads)    
Type of Study: Original Research | Subject: Medical Physics
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA



XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Zincircioglu S, Dogan M. Effects of modulation factors in breast cancer treatment with helical tomotherapy. Int J Radiat Res 2021; 19 (2) :251-257
URL: http://ijrr.com/article-1-3639-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 19, Issue 2 (4-2021) Back to browse issues page
International Journal of Radiation Research
Persian site map - English site map - Created in 0.05 seconds with 50 queries by YEKTAWEB 4645