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Evaluation and analysis of radiation exposure to normal tissues during gamma knife radiosurgery for vestibular schwannoma
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| J.A. Lee, S.R. Kim, S.H. Yoon, J.S. Kim, H.J. Yang, G.H. Kim |
| Department of Bio-medical Science, Korea University, Sejong 30019, Korea , yangh@korea.ac.kr |
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Abstract: (801 Views) |
Background: A follow-up study of gamma knife radiosurgery has shown that postoperative radiation necrosis, radiation-induced edema, and malignant metastasis may occur. This may be due to secondary radiation exposure, therefore, it becomes necessary to actively reduce exposure to normal organs. Materials and Methods: In this study, the secondary radiation dose to the surrounding normal organs was measured during gamma-knife radiosurgery for vestibular schwannoma disease. Using a human pediatric phantom and a glass dosimeter, a treatment plan was established according to the tumor volume, and then the exposure dose to important normal organs in both eyes, thyroid gland, sternum, and both lungs was measured. Results: According to this study, the cancer occurrence probability due to secondary exposure was calculated to be 7 cases per 100,000 people up to the case of the eye and thyroid gland. Exposure doses of 100.2±0.79 mGy or more were measured in both eyes, which is approximately 1000 times that of a chest X-ray or a flight from Seoul to New York. This indicates exposure through gamma knife surgery. The dose to the thyroid gland was 12.7±0.05 mGy, which exceeds the effective dose of 10 mSv in abdominal computed tomography. Conclusion: By measuring the secondary exposure dose to normal organs during gamma-knife surgery for vestibular schwannoma disease, it was confirmed that the eyes and thyroid gland were exposed dangerously. Therefore, for pediatric patients specifically, a treatment plan that actively reduces secondary exposure is required.
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| Keywords: Gamma knife radiosurgery, secondary radiation exposure, secondary cancer, Vestibular schwannoma. |
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Full-Text [PDF 1778 kb]
(398 Downloads)
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Type of Study: Original Research |
Subject:
Radiation Biology
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