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:: Volume 20, Issue 4 (10-2022) ::
Int J Radiat Res 2022, 20(4): 839-843 Back to browse issues page
Comparison of contrast-enhanced ultrasonography and magnetic resonance imaging in evaluating ovarian tumor blood vessels
M. Yang , X. Liu , H. Su
Abstract:   (736 Views)
Background: Our study was to evaluate the value of contrast-enhanced ultrasonography (CEUS) and contrast-enhanced magnetic resonance imaging (CE-MRI) in analyzing the blood vessels associated with ovarian tumors. Materials and Methods: A total of 100 patients with ovarian tumors underwent CEUS and CE-MRI before surgery. After surgery, the resected ovarian tissues were evaluated via immunohistochemistry to calculate the tumor microvessel density (MVD), and the correlation between the parameters of CEUS and CE-MRI and MVD in ovarian tumors was determined. Results: The MVD level between ovarian tumors was significantly different (p = 0.03); the peak intensity (PI) and area under the curve (AUC) of CEUS parameters in malignant tumors were significantly higher than those in benign tumors (p = 0.03, p = 0.03); and were significantly positively correlated with MVD (r = 0.57, p = 0.00; r = 0.50, p = 0.00). The Ktrans and Ve of CE-MRI parameters in malignant tumors were significantly higher than those in benign tumors (p = 0.01 and p = 0.04), and were also significantly positively correlated with MVD (r = 0.66, p = 0.00; r = 0.55, p = 0.00). Moreover, there was no significant difference between CEUS and CE-MRI in terms of sensitivity (Se), specificity (Sp), negative predictive value (NPV) and positive predictive value (PPV) in malignant ovarian tumors (p > 0.05). Conclusion: Both CEUS and CE-MRI parameters can reflect the MVD level in ovarian tumors; therefore, CEUS is expected to become a viable alternative approach for evaluating ovarian tumors.
 
Keywords: Ovarian tumors, microvessel density, contrast-enhanced ultrasound, contrast-enhanced magnetic resonance imaging.
Full-Text [PDF 773 kb]   (507 Downloads)    
Type of Study: Original Research | Subject: Radiation Biology
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Yang M, Liu X, Su H. Comparison of contrast-enhanced ultrasonography and magnetic resonance imaging in evaluating ovarian tumor blood vessels. Int J Radiat Res 2022; 20 (4) :839-843
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Volume 20, Issue 4 (10-2022) Back to browse issues page
International Journal of Radiation Research
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