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AWT IMAGE

AWT IMAGE
:: Volume 21, Issue 3 (6-2023) ::
Int J Radiat Res 2023, 21(3): 537-543 Back to browse issues page
Significance of magnetic resonance zoomed imaging with parallel transmission intravoxel incoherent motion imaging, ultrasonography and dual-energy computed tomography imaging in the differential diagnosis of benign thyroid nodule and papillary thyroid carcinoma
Y. He , X. Qi , X. Luo , W. Wang , H. Yang , M. Xu , X. Wu , W. Fan
Department of Radiology, Ma’anshan People's Hospital, Maanshan, Anhui, 243000, China , yongshenghe1431@163.com
Abstract:   (1213 Views)
Background: To assess the use of computed tomography (CT), ultrasonography and magnetic resonance imaging (MRI) in distinguishing papillary thyroid cancer (PTC) from benign thyroid nodules. Materials and Methods: A total of 45 cases with benign thyroid nodules and 75 cases with papillary thyroid cancer were included from our hospital from March 2020 to December 2021. All patients were examined by MRI, ultrasonography and dual-energy CT. The outcomes of the two groups' MRI, CT and ultrasonography scans were compared. Results: The benign nodule group had significantly higher pure diffusion coefficient (D) (1.38±0.32 vs 0.95±0.12), perfusion fraction (F) values (17.13±4.35 vs 12.83±2.93) and iodine concentration (IC) plain scan scores (0.96±0.44 vs 0.56±0.37), whereas it had lower IC artery scores (2.65±1.11 vs 3.92±1.22) than those of the PTC group (p<0.001 for all). The Emax value of the PTC group was substantially greater than that of the benign nodule group (62.53±37.93 vs 25.37±8.38, p<0.001), and the percentage of nodules with aspect ratio ≥ 1 was higher in the PTC group than in the benign nodule group (48.0% vs 22.2%, p=0.005). The area under the curve (AUC) for MRI in the diagnosis of PTC patients was 0.885, which was substantially higher than those for ultrasonography (AUC=0.705) and CT exams (AUC=0.753) (p<0.001). Conclusion: MRI, ultrasonography and CT examinations are essential for discriminating between benign thyroid nodules and PTC. MRI has better diagnostic accuracy than the other two tests.
Keywords: Papillary thyroid carcinoma, benign thyroid nodules, ZOOMit IVIM imaging, ultrasonography, dual-energy CT imaging.
Full-Text [PDF 1031 kb]   (612 Downloads)    
Type of Study: Original Research | Subject: Radiation Biology
References
1. Chinese Society of Endocrinology, Chinese Medical Association Surgery Branch Endocrinology Group, China Anti-cancer Association, Chinese Society of Nuclear Medicine. (2013) Guidelines for diagnosis and treatment of thyroid nodules and differentiated thyroid carcinoma. Chinese Journal of Nuclear Medicine and Molecular Imaging, 33: 96-115.
2. Chen F, Wu K, Xu MX, Yang Y (2017) Meta-analysis of risk factors for thyroid cancerbased on case-control studies. Chinese Jouranl of Endemiology, 36: 250-256.
3. Lubitz CC and Sosa JA (2016) The changing landscape of papillary thyroid cancer: Epidemiology, management, and the implications for patients. Cancer, 122(24): 3754-3759. [DOI:10.1002/cncr.30201] [PMID]
4. Lee CY, Kim SJ, Ko KR, et al. (2014) Predictive factors for extrathyroidal extension of papillary thyroid carcinoma based on preoperative sonography. J Ultrasonography Med, 33(2): 231-8. [DOI:10.7863/ultra.33.2.231] [PMID]
5. Lin Y, Lai S, Wang P, et al. (2022) Performance of current ultrasound-based malignancy risk stratification systems for thyroid nodules in patients with follicular neoplasms. Eur Radiol, 32(6): 3617-3630. [DOI:10.1007/s00330-021-08450-3] [PMID] []
6. Martens RM, Noij DP, Ali M, et al. (2019) Functional imaging early during (chemo)radiotherapy for response prediction in head and neck squamous cell carcinoma; a systematic review. Oral Oncol, 88: 75-83. [DOI:10.1016/j.oraloncology.2018.11.005] [PMID]
7. Bonjoc KJ, Young H, Warner S, et al. (2020) Thyroid cancer diagnosis in the era of precision imaging. J Thorac Dis, 12(9): 5128-5139. [DOI:10.21037/jtd.2019.08.37] [PMID] []
8. Li M, Zheng X, Gao F, et al. (2016) Spectral CT imaging of intranodular hemorrhage in cases with challenging benign thyroid nodules. Radiol Med, 121(4): 279-290. [DOI:10.1007/s11547-015-0601-6] [PMID]
9. Le Bihan D, Breton E, Lallemand D, et al. (1986) MRimaging of intravoxel incoherent motions: application to diffusion and perfusion inneurologic disorders. Radiology, 161(2): 401-7. [DOI:10.1148/radiology.161.2.3763909] [PMID]
10. Sim KC, Park BJ, Han NY, et al. (2020) Efficacy of ZOOMit coronal diffusion-weighted imaging and MR texture analysis for differentiating between benign and malignant distal bile duct strictures. Abdom Radiol (NY), 45(8): 2418-2429. [DOI:10.1007/s00261-020-02625-0] [PMID]
11. Ai ZD, Hou J, Li FP, et al. (2017) Intravoxel incoherent motion diffusion weighted magnetic resonance imaging for differentiation between benign and malignant thyroid nodules. Chinese Journal of Magnetic Resonance Imaging, 8(10): 742-747.
12. He ZZ, Zhou QQ, Yu YS, et al. (2020) Evaluation of thyroid gland image quality by conventional and ZOOMit DWI. Chinese Computed Medical Imaging, 26(4): 324-328.
13. Tan H, Chen J, Xu QZ, et al. (2016) Differentiation of benign and malignant thyroid nodules using intravoxel incoherent motion. Chinese Journal of Medical Imaging, 24(3): 166-169, 174.
14. Ito Y, Fujii K, Murase T, et al. (2017) Striated duct adenoma presenting with intra-tumoral hematoma and papillary thyroid carcinoma-like histology. Pathol Int, 67(6): 316-321. [DOI:10.1111/pin.12534] [PMID]
15. Rago T, Scutari M, Loiacono V, et al. (2017) Low elasticity of thyroid nodules on ultrasonography elastography is correlated with malignancy, degree of fibrosis, and high expression of Galectin-3 and Fibronectin-1. Thyroid, 27(1): 103-110. [DOI:10.1089/thy.2016.0341] [PMID]
16. Liu PQ, Liu ZL, Wu KLg, et al. (2017) Value of SWE and real-time tissue elastography in the differential diagnosis of benign and malignant thyroid nodules. Chinese Journal of Operative Procedures of General Surgery, (Electronic Edition), 11(05): 393-396.
17. Ao LJ and Liu YL (2020) Application value of shear wave elastography in differential diagnosis of benign and malignant thyroid nodules. Journal of Diseases Monitor and Control, 14(02): 89-93.
18. Han ZJ, Lei ZK, Chen WH, Luo DC (2014) Value of sonography and CT in the preoperative evaluation of cervical lymph node metastasis for papillary thyroid carcinoma. Journal ofChina Clinic Medical Imaging, 25(11): 804-806.
19. Gao SY, Zhang XY, Wei W, et al. (2016) Identification of benign and malignant thyroid nodules by in vivo iodine concentration measurement using single-source dual energy CT: A retrospective diagnostic accuracy study. Medicine, (Baltimore) 95(39): e4816. [DOI:10.1097/MD.0000000000004816] [PMID] []
20. Seidler M, Forghani B, Reinhold C, et al. (2019) Dual-energy CT texture analysis with machine learning for the evaluation and characterization of cervical lymphadenopathy. Comput Struct Biotechnol J, 17: 1009-1015. [DOI:10.1016/j.csbj.2019.07.004] [PMID] []
21. Li L, Wang Y, Luo DH, et al. (2017) Diagnostic value of single-source dual-energy spectral computed tomography for papillary thyroid microcarcinomas. J Xray Sci Technol 25(5): 793-802. [DOI:10.3233/XST-16242] [PMID]
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He Y, Qi X, Luo X, Wang W, Yang H, Xu M, et al . Significance of magnetic resonance zoomed imaging with parallel transmission intravoxel incoherent motion imaging, ultrasonography and dual-energy computed tomography imaging in the differential diagnosis of benign thyroid nodule and papillary thyroid carcinoma. Int J Radiat Res 2023; 21 (3) :537-543
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Volume 21, Issue 3 (6-2023) Back to browse issues page
International Journal of Radiation Research
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