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:: Volume 22, Issue 2 (4-2024) ::
Int J Radiat Res 2024, 22(2): 421-427 Back to browse issues page
A new approach to optimize the genipin gel dosimeter formulation
S.M.M. Abtahi , F. Bahrami , D. Sardari
Physics Department, Imam Khomeini International University, Qazvin, Iran , sm.abtahi@sci.ikiu.ac.ir
Abstract:   (128 Views)
Background: In this work, we investigated the effect of adding 0.3% w/w of the non-toxic substance agarose to the dosimeter formulation of genipin radiochromic gel, which was named LCA-GENA (Low Concentration Agarose-GENipin and Agarose) gel dosimeter.  Materials and Methods: A compact linear accelerator with a beam quality of 6 MV and a dose rate of  200 cGy/min irradiated the produced gel dosimeters in a dose range of 0-10 Gy. A UV-Visible spectrophotometer was used to read out the irradiated gel dosimeters. Calibration curves for both absorbance peak and area-under-spectrum responses were investigated. Furthermore, the physical and radiological characteristics of the new formulation were investigated. Results: The results showed that the dose sensitivity of the LCA-GENA gel dosimeter under the irradiated conditions is (8.4 ± 0.15) × 10-3 cm-1 Gy-1. Results showed adding the abovementioned percentage of agarose will increase the melting point of the genipin gel dosimeter from 24°C to 28°C. Also, an investigation of the radiological properties of the novel formulation revealed that this radiochromic gel is water equivalent. Conclusion: From the obtained results, it is verified that adding 0.3% w/w agarose to the genipin gel dosimeter leads to an increase in the melting point of the original genipin gel dosimeter, easier fabrication, and lower price than that of higher agarose concentrations. The mentioned features make this gel suitable for dosimetry applications in clinical and radiotherapy environments.
Keywords: Radiochromic gel dosimeter, dose sensitivity, GENA, radiological properties.
Full-Text [PDF 667 kb]   (50 Downloads)    
Type of Study: Original Research | Subject: Radiation Biology
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Abtahi S, Bahrami F, Sardari D. A new approach to optimize the genipin gel dosimeter formulation. Int J Radiat Res 2024; 22 (2) :421-427
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Volume 22, Issue 2 (4-2024) Back to browse issues page
International Journal of Radiation Research
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