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Dosimetric impact of Acuros XB over Anisotropic analytical algorithm in kilo voltage Cone-beam CT based treatment planning
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C.O. Clinto   , B. Bindhu |
| Department of Physics, Noorul Islam Centre for Higher Education, Kumaracoil, Tamil Nadu, India , clintoco@gmail.com |
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Abstract: (79 Views) |
Background: The Cone beam computed tomography (CBCT)-based planning is an effective approach and can act as an indicator for adaptive radiotherapy. This study assesses the dosimetric impact of Acuros in comparison to the anisotropic analytical algorithm (AAA) in kilo voltage-CBCT dose calculation using protocol-specific calibration and Hounsfield unit (HU) override techniques. Materials and Methods: In this study, three anatomical sites—pelvis, head and neck and thorax—were considered for evaluation. The anthropomorphic phantoms used were the BrainLab pelvis phantom, Accuray’s head phantom, and an indigenously developed thorax phantom, respectively. Results: In the prostate case, the maximum difference between AAA and Acuros was 0.3% for protocol-specific calibration and 0.6% for HU override. In the head and neck case, the differences were 1.1% and 0.9% for the respective techniques. In the study on lung tumors, there was an 8% underestimation in the ipsilateral lung mean dose for the protocol-specific CBCT calibration with Acuros, compared to a 0.6% overestimation with AAA. Compared with the EBT3 film dose profile, the mismatch was evident, with Acuros showing greater accuracy over AAA. Conclusion: The dosimetric accuracy of CBCT-based dose calculation is affected by the choice of dose calculation algorithm for a given image quality and technique. The effect of the dose calculation algorithm depends on site-specific inhomogeneity: it is least for the pelvic region and significant for the head and neck and thorax regions. Acuros appears to be much more effective than AAA in accounting for the image quality differences of CBCT. |
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| Keywords: Cone-beam computed tomography, Acuros XB, Anisotropic analytical algorithm. |
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Full-Text [PDF 842 kb]
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Type of Study: Original Research |
Subject:
Radiation Biology
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