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Radiologic value of computerized tomography angiography (CTA) for assessment of carotid artery Tortuosity Index and its impact on stroke recovery
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Y. Wang   , W. Cui |
| Department of Neurology, Shahe Hospital Changping District, Beijing 102206, China , ssamsca2001@163.com |
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Abstract: (223 Views) |
Background: This study investigated the relationship between extracranial internal carotid artery (EICA) and extracranial carotid artery (ECA) tortuosity and clinical prognosis in acute anterior circulation ischemic stroke (AIS). Materials and Methods: We retrospectively analyzed 201 patients with anterior circulation AIS who underwent head and neck CT angiography (CTA) between January–December 2023.CTA was performed using a Discovery CT750 HD scanner (GE Medical Systems), with scanning extending from the aortic arch to the skull vertex. Iopromide contrast agent (37g iodine/100ml) was administered intravenously. Images were reconstructed at 0.63-mm slice thickness using multiplanar reformation (MPR) and 3D volume rendering (VR). Results: Tortuosity Index (TI) of EICA and ECA were independent predictors of poor 90-day prognosis (modified Rankin Scale [mRS] ≥3) in multivariate regression (Model I: EICA OR=1.038, P=0.007.ECA OR=1.052, P=0.015). ROC analysis showed ECA-TI≥12.5 predicted poor prognosis with higher specificity (AUC=0.623,sensitivity 55.6%,specificity 68.3%) than EICA-TI ≥14.5 (AUC=0.601,sensitivity 61.9%,specificity60.7%). Conclusions: Increased EICA/ECA tortuosity independently correlates with poor AIS outcomes, with ECA-TI being a superior prognostic indicator. |
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| Keywords: Carotid arteries, stroke prognosis, intracranial arteriosclerosis, x-ray computed, risk factors. |
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Full-Text [PDF 842 kb]
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Type of Study: Original Research |
Subject:
Radiation Biology
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