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Dosimetric comparison of whole breast radiotherapy using field in field and conformal radiotherapy techniques in early stage breast cancer
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G. Yavas   , C. Yavas , H. Acar |
| , guler.aydinyavas@gmail.com |
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Abstract: (9127 Views) |
| Background: We aimed to compare field-in-field
technique (FIF) with conformal tangential field radiotherapy
(CRT) in terms of dosimetric benefits for early
stage breast cancer radiotherapy. Materials and
Methods: Twenty consecutive left-side breast cancer
patients who underwent breast-conserving surgery
were included to the study. For each patient, two
different treatment plans were created for the entire
breast. FIF plans and CRT plans were compared for
doses in the planning target volume (PTV), the organ
at risk (OAR) volume including ipsilateral lung, heart,
left ascending coronary artery (LAD) and the
contralateral breast, the homogeneity index (HI), and
the monitor unit (MU) counts required for the
treatment. Paired samples t-test was used for
statistical analysis. Results: The FIF technique
significantly reduced the maximum dose of the PTV
as well as the mean doses of the heart, LAD,
ipsilateral lung and the contralateral breast (p values
were <0.001 for each). When the OAR volumes
irradiated with 2, 5, 10, 20, 30 and 40 Gy were
compared, the results were in favor of the FIF
technique. The volume receiving <20 Gy of the
prescription dose for the ipsilateral lung was
significantly decreased using FIF technique
(p<0.001). FIF technique allowed us more homogenous
dose distribution with lower MUs. Conclusion:
The FIF technique provided better dose distribution in
the PTV and significantly reduced the doses in the
OAR. Considering the lower MUs required for
treatment the FIF technique seems to be more
advantageous than CRT during whole breast
irradiation. Iran. J. Radiat. Res., 2012 10(3‐4): 131‐138
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| Keywords: Breast cancer, conformal radiotherapy, dose volume histograms, field-in-field technique. |
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Full-Text [PDF 346 kb]
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Type of Study: Original Research |
Subject:
Radiation Biology
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