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Comparison of conventional and 3D conformal treatments using linac energies for prostate cancer
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S.A. Vaezzadeh   , M. Allahverdi , H.A. Nedaie , M. Aghili , M. Esfehani |
| , avaezzadeh@razi.tums.ac.ir |
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Abstract: (10090 Views) |
| Background: To evaluate the dosimetric difference
between conventional and three-dimensional
conformal Radiotherapy (3D-CRT) using 6 and 18 MV
X-ray photons. Materials and Methods: Computed
tomography scans of 26 pelvic patients were
acquired and transferred to the 3D treatment
planning system. For each patient, 8 Conventional
plans (3, 4, 5 and 6 Fields) and one 3D-CRT plan
were prepared using 6 and 18 MV photon energies.
The minimum dose (Dmin), maximum dose (Dmax) and
mean dose (Dmean) to target (PTV) and organs at risk
(OAR), Integral dose, Homogeneity Index and
Conformity Index were compared for each plan. Also,
Experimental measurements were performed using
farmer ionization chamber on a patient based pelvic
phantom. Results: On Average, six-field (6F1) plans,
offer minimum dose to critical organs and sufficient
dose to prostate. Increasing the beam energy lead to
a decrease in Dmean of the bladder and femoral
heads, as well as Dmax of PTV. The CI and ID were
decreased by 4% and 11% respectively with
increasing the energy and the number of beams.
Experimental measurements were also in good
agreement with calculations. 3D-CRT reduced Dmean
of bladder, rectum and femoral heads and also CI
and ID were significantly improved by 44.6% and
30.8%, respectively. Conclusion: Increasing the
photon energy and number of beams, improve the
treatment parameters of bladder, femoral heads and
PTV, except the rectum. 3D-CRT offered the most
conformity in the delivery doses to the prostate while
sparing dose to OARs, uninvolved structures with
lower integral dose. Iran. J. Radiat. Res., 2012 10(3‐4):
145‐150
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| Keywords: Conventional, 3D-conformal radiotherapy, conformity index, integral dose, prostate cancer. |
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Full-Text [PDF 383 kb]
(5537 Downloads)
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Type of Study: Original Research |
Subject:
Radiation Biology
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