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:: Volume 21, Issue 4 (10-2023) ::
Int J Radiat Res 2023, 21(4): 663-673 Back to browse issues page
Implementation of geant4 application for tomography emission Monte Carlo Code in the calculation of dose distribution in external radiation therapy
A.B. Yeke Dehghan , A. Mostaar , P. Azadeh
Department of Medical Physics and Biomedical Engineering, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran , mostaar@sbmu.ac.ir
Abstract:   (692 Views)
Background: The "Geant4 Application for Tomography Emission" (GATE) toolkit comprises advanced open-source Monte Carlo (MC) code for use in ‎medical imaging and radiotherapy simulations. This study aimed to verify the GATE toolkit results against a water phantom and then to show the dose calculation capabilities of the GATE for radiotherapy. The results were compared with three dose calculation algorithms using patients' Computerized Tomography (CT) data.‎ Materials and Methods: A Linac with a 6 MV photon beam was simulated in the GATE code. The ‎code was verified, head CT images of three patients were inserted into the GATE as realistic ‎phantoms‎, and simulations were performed for different field sizes and angles. The Percent ‎Depth Doses (PDDs) and transverse profiles were extracted from the GATE simulation and ‎calculation ‎algorithms. Their results were ‎compared regarding the Dose Difference (DD) and gamma index for the PDDs and the Full Width at Half Maximum (FWHM) for the profiles. ‎Results: Using the patient CT data for the PDDs, the ‎gamma pass rate with 3%/3 mm criteria in the comparison between the GATE ‎simulation and ‎algorithms for all fields ranged from 89.4% to ‎‎98.8%, with an average of 92.8%. The ‎extracted FWHMs from the GATE and algorithms were in good agreement, and their differences ranged from 0.1 to 1.2 mm. Conclusions: The GATE MC toolkit has good potential for implementation in radiotherapy Treatment Planning Systems (TPS) for dose calculations.
Keywords: GATE, geant4, Monte Carlo Code, photon beam.
Full-Text [PDF 1557 kb]   (429 Downloads)    
Type of Study: Original Research | Subject: Radiation Biology
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Yeke Dehghan A, Mostaar A, Azadeh P. Implementation of geant4 application for tomography emission Monte Carlo Code in the calculation of dose distribution in external radiation therapy. Int J Radiat Res 2023; 21 (4) :663-673
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Volume 21, Issue 4 (10-2023) Back to browse issues page
International Journal of Radiation Research
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