|
The value of magnetic resonance diffusion weighted imaging sequence and T2 mapping imaging technology in evaluating knee joint defects
|
C.Z. Huang   , C.K. Lin , Q.M. Fu , J.H. Huang , N.L. Jia , Y. Chen |
| Department of Radiological, The second Affiliated Hospital of Hainan Medical University, Hainan, China , 724897505@qq.com |
|
|
Abstract: (1479 Views) |
Background: Diagnosing knee osteoarthritis (KOA) often relies on limited routine methods. This study investigates the efficacy of T2 mapping and Apparent Diffusion Coefficient (ADC) values in MRI for enhanced assessment of cartilage damage in KOA, focusing on their correlation with pain severity. Materials and Methods: A total of 52 KOA patients (74 knee joints) and 50 healthy individuals (100 knee joints) were assessed from May 2022 to June 2023. Both groups underwent MRI with Diffusion Weighted Imaging (DWI) sequence and T2 mapping to analyze ADC and T2 mapping values across femoral condyle, tibial plateau, and patellar joint surfaces, and their correlation with pain levels. Results: The KOA group showed significantly higher ADC and T2 mapping values in all examined areas compared to the control group (P<0.05). These values were also higher in advanced stages of cartilage degeneration and correlated positively with increased pain scores (P<0.05). Conclusion: MRI utilizing DWI and T2 mapping provides a quantitative reflection of knee joint cartilage degeneration in KOA. These methods show a positive correlation with pain severity, suggesting their potential for more accurate KOA diagnostics and assessment. |
|
| Keywords: Knee osteoarthritis (KOA), magnetic resonance imaging (MRI), diffusion-weighted imaging (DWI), T2 mapping, cartilage degeneration. |
|
|
Full-Text [PDF 609 kb]
(347 Downloads)
|
|
Type of Study: Original Research |
Subject:
Radiation Biology
|
|
|
|
|
|
|
| References |
1. Tan H, Kang W, Fan Q, et al. (2023) Intravoxel incoherent motion diffusion-weighted MR imaging findings of infrapatellar fat pad signal abnormalities: Comparison between symptomatic and asymptomatic knee osteoarthritis. Academic Radiology, 30(7): 1374-1383. [ DOI:10.1016/j.acra.2022.11.010] 2. Barendregt AM, Mazzoli V, van Gulik EC, et al. (2020) Juvenile idiopathic arthritis: Diffusion-weighted MRI in the assessment of arthritis in the knee. Radiology, 295(2): 373-380. [ DOI:10.1148/radiol.2020191685] 3. Banjar M, Horiuchi S, Gedeon DN, Yoshioka H (2022) Review of quantitative knee articular cartilage MR imaging. Magnetic Resonance in Medical Sciences, 21(1): 29-40. [ DOI:10.2463/mrms.rev.2021-0052] 4. Luo P, Hu W, Xu R, et al. (2023) Enabling early detection of knee osteoarthritis using diffusion-relaxation correlation spectrum imaging. Clinical Radiology, 78(9): e681-e687. [ DOI:10.1016/j.crad.2023.05.013] 5. Ikuta F, Takahashi K, Hashimoto S, et al. (2020) Effect of physical therapy on early knee osteoarthritis with medial meniscal posterior tear assessed by MRI T2 mapping and 3D-to-2D registration technique: A prospective intervention study. Modern Rheumatology, 30(4): 738-747. [ DOI:10.1080/14397595.2019.1646193] 6. Leichtenberg CS, van Tol FR, Gademan M, et al. (2021) Are pain, functional limitations and quality of life associated with objectively measured physical activity in patients with end-stage osteoarthritis of the hip or knee? Knee, 29: 78-85. [ DOI:10.1016/j.knee.2020.12.019] 7. Schutz U, Martensen T and Kleiner S, et al. (2022) T2*-mapping of knee cartilage in response to mechanical loading in alpine skiing: A feasibility study. Diagnostics, 12(6): 1391. [ DOI:10.3390/diagnostics12061391] 8. Verschueren J, Eijgenraam SM, Klein S, et al. (2021) T(2) mapping of healthy knee cartilage: multicenter multivendor reproducibility. Quantitative Imaging in Medicine and Surgery, 11(4): 1247-1255. [ DOI:10.21037/qims-20-674] 9. Tsai PH, Wong CC, Chan WP (2022) Radial T2* mapping reveals early meniscal abnormalities in patients with knee osteoarthritis. European Radiology, 32(8): 5642-5649. [ DOI:10.1007/s00330-022-08641-6] 10. Viren T, Saarakkala S, Kaleva E, et al. (2009) Minimally invasive ultrasound method for intra-articular diagnostics of cartilage degeneration. Ultrasound in Medicine and Biology, 35(9): 1546-1554. [ DOI:10.1016/j.ultrasmedbio.2009.04.004] 11. Yang Z, Xie C, Ou S, et al. (2022) Cutoff points of T1 rho/T2 mapping relaxation times distinguishing early-stage and advanced osteoarthritis. Archives of Medical Science, 18(4): 1004-1015. [ DOI:10.5114/aoms/140714] 12. Luo P, Hu W, Jiang L, et al. (2022) Evaluation of articular cartilage in knee osteoarthritis using hybrid multidimensional MRI. Clinical Radiology, 77(7): e518-e525. [ DOI:10.1016/j.crad.2022.03.002] 13. Murakami K, Arai Y, Ikoma K, et al. (2018) Total resection of any segment of the lateral meniscus may cause early cartilage degeneration: Evaluation by magnetic resonance imaging using T2 mapping. Medicine, 97(23): e11011. [ DOI:10.1097/MD.0000000000011011] 14. Bachmann GF, Basad E, Rauber K, et al. (1999) Degenerative joint disease on MRI and physical activity: a clinical study of the knee joint in 320 patients. European Radiology, 9(1): 145-152. [ DOI:10.1007/s003300050646] 15. Chan WP, Lang P, Stevens MP, et al. (1991) Osteoarthritis of the knee: comparison of radiography, CT, and MR imaging to assess extent and severity. American Journal of Roentgenology, 157(4): 799-806. [ DOI:10.2214/ajr.157.4.1892040] 16. Nishioka H, Hirose J, Okamoto N, et al. (2015) Evaluation of the relationship between T1rho and T2 values and patella cartilage degeneration in patients of the same age group. European Journal of Radiology, 84(3): 463-468. [ DOI:10.1016/j.ejrad.2014.11.015] 17. Lindner D, Chechik Y, Beer Y, et al. (2022) T2 Mapping Values in Postmeniscectomy Knee Articular Cartilage after Running: Early Signs of Osteoarthritis? Journal of Knee Surgery, 35(7): 739-749. [ DOI:10.1055/s-0040-1718596] 18. Shi L, Wang K, Yu J, et al. (2021) Relationship between magnetic resonance T2-mapping and matrix metalloproteinase 1, 3 in knee osteoarthritis. Indian Journal of Orthopaedics, 55(4): 974-982. [ DOI:10.1007/s43465-020-00293-2] 19. Roth C, Hirsch FW, Sorge I, et al. (2023) Preclinical cartilage changes of the knee joint in adolescent competitive volleyball players: A prospective T2 mapping study. Rofo-Fortschritte Auf Dem Gebiet Der Rontgenstrahlen Und Der Bildgebenden Verfahren, 195(10): 913-923. [ DOI:10.1055/a-2081-3245] 20. Mittal S, Pradhan G, Singh S, Batra R (2019) T1 and T2 mapping of articular cartilage and menisci in early osteoarthritis of the knee using 3-Tesla magnetic resonance imaging. Polish Journal of Radiology, 84: e549-e564. [ DOI:10.5114/pjr.2019.91375] |
|
| Send email to the article author |
|
|
|
| Add your comments about this article |
|
|
|
|
Huang C, Lin C, Fu Q, Huang J, Jia N, Chen Y. The value of magnetic resonance diffusion weighted imaging sequence and T2 mapping imaging technology in evaluating knee joint defects. Int J Radiat Res 2024; 22 (2) :271-275 URL: http://ijrr.com/article-1-5391-en.html
|
