The value of magnetic resonance diffusion weighted imaging sequence and T2 mapping imaging technology in evaluating knee joint defects

Huang, C.Z.; Lin, C.K.; Fu, Q.M.; Huang, J.H.; Jia, N.L.; Chen, Y.

doi:10.61186/ijrr.22.2.271

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Volume 22, Issue 2 (4-2024) Int J Radiat Res 2024, 22(2): 271-275 | Back to browse issues page

‎ 10.61186/ijrr.22.2.271

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Huang C, Lin C, Fu Q, Huang J, Jia N, Chen Y. The value of magnetic resonance diffusion weighted imaging sequence and T2 mapping imaging technology in evaluating knee joint defects. Int J Radiat Res 2024; 22 (2) :271-275
URL: http://ijrr.com/article-1-5391-en.html

The value of magnetic resonance diffusion weighted imaging sequence and T2 mapping imaging technology in evaluating knee joint defects

C.Z. Huang

, C.K. Lin

, Q.M. Fu

, J.H. Huang

, N.L. Jia

, Y. Chen

Department of Radiological, The second Affiliated Hospital of Hainan Medical University, Hainan, China , 724897505@qq.com

Abstract: (2058 Views)

Background: Diagnosing knee osteoarthritis (KOA) often relies on limited routine methods. This study investigates the efficacy of T2 mapping and Apparent Diffusion Coefficient (ADC) values in MRI for enhanced assessment of cartilage damage in KOA, focusing on their correlation with pain severity. Materials and Methods: A total of 52 KOA patients (74 knee joints) and 50 healthy individuals (100 knee joints) were assessed from May 2022 to June 2023. Both groups underwent MRI with Diffusion Weighted Imaging (DWI) sequence and T2 mapping to analyze ADC and T2 mapping values across femoral condyle, tibial plateau, and patellar joint surfaces, and their correlation with pain levels. Results: The KOA group showed significantly higher ADC and T2 mapping values in all examined areas compared to the control group (P<0.05). These values were also higher in advanced stages of cartilage degeneration and correlated positively with increased pain scores (P<0.05). Conclusion: MRI utilizing DWI and T2 mapping provides a quantitative reflection of knee joint cartilage degeneration in KOA. These methods show a positive correlation with pain severity, suggesting their potential for more accurate KOA diagnostics and assessment.

Keywords: Knee osteoarthritis (KOA), magnetic resonance imaging (MRI), diffusion-weighted imaging (DWI), T2 mapping, cartilage degeneration.

Full-Text [PDF 609 kb] (604 Downloads)

Type of Study: Original Research | Subject: Radiation Biology

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