Department of Ultrasound, Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine, Zhuhai, China , chenminzhi_zhuhai@163.com
Abstract: (25 Views)
Background:Ovarian Malignant Müllerian Mixed Tumor (MMMT), also named ovarian carcinosarcoma (OCS), is a rare and aggressive biphasic malignancy with malignant epithelial and mesenchymal components. Advanced magnetic resonance imaging (MRI) techniques like quantitative T2 mapping enable non-invasive tissue microstructural assessment, their diagnostic value for ovarian MMMT requires further elucidation with clinical case evidence. Case presentation: A 78-year-old female presented with chronic constipation and a pelvic mass. Imaging revealed a large, heterogeneous pelvic mass with peritoneal and omental involvement. Quantitative MRI analysis revealed a T2 mapping value of 148±18 ms and a low apparent diffusion coefficient (ADC) value of 0.98±0.08×10-3 mm2/s. Histopathological examination confirmed ovarian MMMT with heterologous chondrosarcoma components. Conclusion: This case demonstrates that quantitative MRI parameters, especially T2 mapping, can reflect the high-grade malignant microstructural features of ovarian MMMT. T2 mapping serves as a valuable non-invasive biomarker for characterizing this rare gynecological malignancy, potentially aiding in the differentiation of benign and malignant ovarian lesions and assessment of tumor aggressiveness.
Wang X, Sun G, Zhang H, Chen M. Computerized tomography and magnetic resonance imaging features with quantitative T2 mapping of a primary malignant müllerian mixed tumor of the ovary: A case report. Int J Radiat Res 2026; 24 (2) :567-572 URL: http://ijrr.com/article-1-7080-en.html